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The ectodomain of TR binds AβO with a high affinity. ApoE, TR#2, and ovalbumin applied to the flow phase and their binding to AβO (prepared from the peptide Aβ1-42) immobilized on the chip was analyzed in real time. Shown are representative SPR response curves elicited by indicated protein ligands with a series of concentrations. RU, Response Unit.
