Figure 1. MicroRNAs associated with common cytogenetic aberrations in CLL.
CLL patients an be categorized in different cytogenetic subgroups based on prognosis: del13 is a good prognostic factor, tri12 and NL cyto/FISH are intermediate prognostic factors and del11q and del17p are associated with poor prognosis. The protein-coding and non-coding genes between brackets in the blue boxes represent targets of the cytogenetic aberration; the miRNAs highlighted in the yellow boxes represent miRNAs that have been associated with the specific cytogenetic aberration.