Table 1.

Description of the two-level classification of methodological concerns from the HAS guidelines.

Level 1	Level 2
Structural choices	Economic analysis and choice of outcome criterion
	Time horizon
	Comparison of strategies
	Perspective
Measurement and valuation of health states and costs	Costs Measurement and calculation Cost type Valuation
	Health states Measurement (methods and data) Valuation
Modelling	Transition estimates Data extrapolation Estimation method Reporting Efficacy data source
	Modelled population
	Model structure
	Programming errors
Study objective	–
Results presentation and sensitivity analyses	Sensitivity analyses Deterministic/probabilistic Scenario
	Presentation
	Validity (internal and external) and study limitations