Table 3.
Effects of GTE on the body weight, diet intake, food efficiency, and serum biochemical parameters in HED-fed rats.
| C | HE | 1X | 2X | |
|---|---|---|---|---|
| Total food intake (g)/rat | 1386.7 ± 13.4a | 1382.0 ± 18.9a | 1377.9 ± 18.0a | 1376.2 ± 19.1a |
| Increase of BW/rat | 221.2 ± 17.7a | 306.3 ± 19.6c | 252.5 ± 24.7b | 247.2 ± 16.6b |
| FCE (%) | 15.9 ± 1.3a | 22.2 ± 1.4c | 18.4 ± 1.8b | 17.9 ± 1.3b |
| TG (mg/dl) | 44.3 ± 3.0a | 79.0 ± 10.3c | 55.1 ± 7.5b | 52.1 ± 3.9b |
| TC (mg/dl) | 42.0 ± 6.4a | 69.5 ± 7.8d | 61.2 ± 6.6 c | 53.3 ± 7.5 b |
| LDL (mg/dl) | 5.5 ± 0.7a | 7.8 ± 1.2b | 6.3 ± 1.6a | 6.0 ± 0.9a |
| HDL (mg/dl) | 20.1 ± 4.0c | 13.4 ± 1.4a | 16.0 ± 1.3b | 16.1 ± 1.5b |
| FFA (μM) | 3.2 ± 1.1a | 4.9 ± 0.9b | 3.9 ± 0.5a | 3.5 ± 0.4a |
| AST (U/L) | 126.9 ± 39.4a | 224.1 ± 79.3b | 171.9 ± 13.7a | 163.1 ± 15.2a |
| ALT (U/L) | 33.1 ± 4.6a | 58.6 ± 9.7c | 47.9 ± 6.7b | 43.1 ± 11.6b |
Control, vehicle control; HE, HED vehicle control; 1X, HED with 77.5 mg/kg/day of GTE; 2X, HED with 155 mg/kg/day of GTE. All values are the mean ± SEM (n = 10 rats/group). Different superscript letters (a, b, c) indicate a significant difference at p < 0.05 by a one-way ANOVA with Tukey’s post-hoc test. BW, body weight; FCE, food conversion efficiency (Increase of BW/Total calories intake); TG, triacylglycerol; TC total cholesterol; FFA, free fatty acids; AST, aspartate transaminase; ALT, alanine transaminase.