Table 2.

List of total plasm miRNAs meeting the 20% FDR criteria using the Benjamini–Hochberg procedure.

Comparison between normal, MMVD and MMVD-CHF groups	cfa-let-7a, cfa-miR-105a, cfa-miR-105b, cfa-miR-126, cfa-miR-1271, cfa-miR-129, cfa-miR-1307, cfa-miR-133a, cfa-miR-138b, cfa-miR-139, cfa-miR-142, cfa-miR-149, cfa-miR-181d, cfa-miR-186, cfa-miR-196a, cfa-miR-196b, cfa-miR-200b, cfa-miR-202, cfa-miR-212, cfa-miR-217, cfa-miR-218, cfa-miR-219-5p, cfa-miR-29a, cfa-miR-30b, cfa-miR-325, cfa-miR-329a, cfa-miR-335, cfa-miR-338, cfa-miR-345, cfa-miR-34c, cfa-miR-363, cfa-miR-374b, cfa-miR-376a, cfa-miR-379, cfa-miR-380, cfa-miR-382, cfa-miR-384, cfa-miR-421, cfa-miR-429, cfa-miR-487a, cfa-miR-489, cfa-miR-491, cfa-miR-495, cfa-miR-496, cfa-miR-504, cfa-miR-514, cfa-miR-545, cfa-miR-551a, cfa-miR-568, cfa-miR-578, cfa-miR-592, cfa-miR-708, cfa-miR-759, cfa-miR-761, cfa-miR-764, cfa-miR-802, cfa-miR-872, cfa-miR-99b
FDR-adjusted p-value ≤0.042
Comparison between MMVD and MMVD-CHF groups
FDR-adjusted p-value ≤0.039
	cfa-let-7f, cfa-let-7g, cfa-miR-105a, cfa-miR-105b, cfa-miR-126, cfa-miR-1307, cfa-miR-133a, cfa-miR-139, cfa-miR-141, cfa-miR-142, cfa-miR-149, cfa-miR-181d, cfa-miR-1836, cfa-miR-193a, cfa-miR-196a, cfa-miR-200b, cfa-miR-202, cfa-miR-212, cfa-miR-217, cfa-miR-218, cfa-miR-219-5p, cfa-miR-223, cfa-miR-23a, cfa-miR-29a, cfa-miR-30a, cfa-miR-325, cfa-miR-329a, cfa-miR-338, cfa-miR-363, cfa-miR-367, cfa-miR-374b, cfa-miR-376a, cfa-miR-379, cfa-miR-382, cfa-miR-384, cfa-miR-452, cfa-miR-454, cfa-miR-491, cfa-miR-495, cfa-miR-496, cfa-miR-504, cfa-miR-514, cfa-miR-544, cfa-miR-545, cfa-miR-551a, cfa-miR-568, cfa-miR-578, cfa-miR-592, cfa-miR-652, cfa-miR-665, cfa-miR-708, cfa-miR-759, cfa-miR-761, cfa-miR-802, cfa-miR-872, cfa-miR-876, miR-96

Three group comparison was performed using the Kruskal–Wallis test, and two-way comparisons was performed using the Mann–Whitney U-test.

FDR = false discovery rate; MMVD = myxomatous mitral valve disease; MMVD-CHF = heart failure due to MMVD.