Table II.
Linear regression models for HAZ, BMIZ, and WAZ in midchildhood (4-9 years of age)
| HAZ | BMIZ | WAZ | ||||
|---|---|---|---|---|---|---|
| Univariate models | Multivariate models* | Univariate models | Multivariate models* | Univariate models | Multivariate models* | |
| Baseline (6-week) measurements | ||||||
| LAZ† | ||||||
| Beta | 0.33 | 0.47 | 0.04 | 0.16 | 0.25 | 0.42 |
| 95% CI | 0.14 to 0.53 | 0.25 to 0.68 | 0.14 to 0.23 | 0.06 to 0.39 | 0.06 to 0.43 | 0.22 to 0.62 |
| P value | .001 | <.001 | .65 | .15 | .009 | <.001 |
| WAZ† | ||||||
| Beta | 0.06 | 0.12 | 0.35 | 0.53 | 0.28 | 0.46 |
| 95% CI | 0.19 to 0.30 | 0.13 to 0.37 | 0.14 to 0.56 | 0.30 to 0.76 | 0.06 to 0.50 | 0.24 to 0.67 |
| P value | .65 | .33 | .002 | <.001 | .01 | <.001 |
| WLZ† | ||||||
| Beta | −0.34 | −0.05 | 0.28 | 0.64 | −0.02 | 0.43 |
| 95% CI | 0.52 to −0.16 | 0.29 to 0.19 | 0.11 to 0.45 | 0.42 to 0.87 | −0.20 to 0.16 | 0.21 to 0.65 |
| P value | <.001 | .11 | .001 | <.001 | .82 | <.001 |
| Flagellin IgG (adjusted optical density)‡ | ||||||
| Beta | −1.32 | −1.36 | 0.36 | 0.46 | −0.57 | −0.52 |
| 95% CI | −3.12 to 0.48 | −3.11 to 0.38 | −1.15 to 1.87 | −1.10 to 2.02 | −2.15 to 1.00 | −2.09 to 1.04 |
| P value | .15 | .12 | .64 | .56 | .47 | .50 |
| Flagellin IgA (adjusted optical density)‡ | ||||||
| Beta | −0.02 | −0.82 | 0.24 | −0.15 | 0.19 | −0.58 |
| 95% CI | −1.44 to 1.40 | −2.26 to 0.62 | −0.93 to 1.42 | −1.42 to 1.13 | −1.04 to 1.41 | −1.86 to 0.69 |
| P value | .98 | .26 | .68 | .82 | .76 | .36 |
| LPS IgG (adjusted optical density)‡ | ||||||
| Beta | 0.01 | −0.44 | −0.11 | −0.19 | −0.08 | −0.40 |
| 95% CI | −0.84 to 0.86 | −1.28 to 0.41 | −0.81 to 0.60 | −0.94 to 0.55 | −0.81 to 0.66 | −1.14 to 0.34 |
| P value | .99 | .31 | .77 | .60 | .84 | .28 |
| LPS IgA (adjusted optical density)‡ | ||||||
| Beta | −0.61 | −0.93 | −0.06 | −0.08 | −0.41 | −0.61 |
| 95% CI | −1.62 to 0.41 | −1.91 to 0.05 | −0.91 to 0.79 | −0.97 to 0.80 | −1.29 to 0.47 | −1.48 to 0.27 |
| P value | .24 | .06 | .90 | .86 | .35 | .17 |
| Change in anthropometry from 6 to 52 weeks | ||||||
| LAZ† | ||||||
| Beta | 0.19 | 0.40 | 0.13 | 0.19 | 0.21 | 0.40 |
| 95% CI | −0.01 to 0.38 | 0.20 to 0.61 | −0.05 to 0.30 | −0.02 to 0.40 | 0.03 to 0.39 | 0.21 to 0.59 |
| P value | .06 | <.001 | .16 | .08 | .02 | <.001 |
| WAZ† | ||||||
| Beta | 0.28 | 0.35 | 0.21 | 0.32 | 0.33 | 0.45 |
| 95% CI | 0.09 to 0.48 | 0.14 to 0.56 | 0.03 to 0.39 | 0.13 to 0.51 | 0.16 to 0.51 | 0.27 to 0.63 |
| P value | .004 | .001 | .02 | <.001 | <.001 | <.001 |
| WLZ† | ||||||
| Beta | 0.33 | 0.29 | 0.07 | 0.38 | 0.27 | 0.45 |
| 95% CI | 0.21 to 0.46 | 0.11 to 0.47 | −0.06 to 0.20 | 0.21 to 0.54 | 0.15 to 0.38 | 0.29 to 0.62 |
| P value | <.001 | .002 | .28 | <.001 | <.001 | <.001 |
Multivariate models for HAZ, BMIZ, and WAZ in mid-childhood adjust for which trial the child originally participated in, treatment arm, maternal height (cm), maternal education (0, 1-7 or ≥8 years), and child's sex and age at follow-up. Multivariate models for BMIZ adjust for which trial the child originally participated in, treatment arm, maternal height (cm), maternal education (0, 1-7 or ≥8 years), and child's sex and age at follow-up. Multivariate models for WAZ adjust for which trial the child originally participated in, treatment arm, maternal height (cm), maternal education (categories), and child's sex and age at follow-up.
Multivariate models with anthropometric indicators as independent variables also include the corresponding anthropometric indicator at 6 weeks or change from 6 to 52 weeks of age, for example, the model reporting the beta parameter for LAZ at 6 weeks adjusts for change in LAZ from 6 to 52 weeks of age, and vice versa.
n = 66 (children from second trial only).