Table III.
Linear regression models for systolic and diastolic blood pressure in midchildhood (4-9 years of age)
| Systolic blood pressure | Diastolic blood pressure | |||
|---|---|---|---|---|
| Univariate models | Multivariate models* | Univariate models | Multivariate models* | |
| Baseline (6-week) measurements | ||||
| LAZ† | ||||
| Beta | 0.24 | 0.44 | 0.43 | 0.60 |
| 95% CI | −1.57 to 2.05 | −1.73 to 2.61 | −0.75 to 1.62 | −0.84 to 2.05 |
| P value | .79 | .69 | .47 | .41 |
| WAZ† | ||||
| Beta | 0.64 | 1.52 | 0.50 | 0.94 |
| 95% CI | −1.50 to 2.79 | −0.87 to 3.91 | −0.90 to 1.89 | −0.65 to 2.52 |
| P value | .55 | .21 | .48 | .24 |
| WLZ† | ||||
| Beta | 0.26 | 2.04 | −0.07 | 0.85 |
| 95% CI | −1.46 to 1.97 | −0.44 to 4.52 | −1.19 to 1.04 | −0.80 to 2.50 |
| P value | .77 | .11 | .90 | .31 |
| Flagellin IgG (adjusted optical density)‡ | ||||
| Beta | −0.97 | 4.58 | 3.60 | 7.36 |
| 95% CI | −15.23 to 13.30 | −12.11 to 21.27 | −6.17 to 13.36 | −4.30 to 19.01 |
| P value | .89 | .58 | .46 | .21 |
| Flagellin IgA (adjusted optical density)‡ | ||||
| Beta | 17.67 | 17.81 | 12.08 | 13.95 |
| 95% CI | 7.51 to 27.82 | 6.50 to 29.1 | 5.10 to 19.07 | 6.14 to 21.76 |
| P value | <.001 | .003 | .001 | .001 |
| LPS IgG (adjusted optical density)‡ | ||||
| Beta | −2.23 | −0.58 | 1.19 | 2.29 |
| 95% CI | −8.84 to 4.38 | −8.19 to 7.02 | −3.36 to 5.74 | −3.05 to 7.63 |
| P value | .50 | .88 | .60 | .39 |
| LPS IgA (adjusted optical density)‡ | ||||
| Beta | −2.21 | −1.71 | −1.34 | −1.39 |
| 95% CI | −10.19 to 5.78 | −10.67 to 7.25 | −6.83 to 4.15 | −7.72 to 4.94 |
| P value | .58 | .70 | .63 | .66 |
| Change in anthropometry from 6 to 52 weeks | ||||
| LAZ† | ||||
| Beta | 0.58 | 0.80 | −0.04 | 0.40 |
| 95% CI | −1.15 to 2.31 | −1.41 to 3.01 | −1.18 to 1.10 | −01.07 to 1.87 |
| P value | .50 | .47 | .95 | .59 |
| WAZ† | ||||
| Beta | 0.62 | 1.10 | 0.17 | 0.55 |
| 95% CI | −1.16 to 2.39 | −0.92 to 3.13 | −0.99 to 1.33 | −0.79 to 1.89 |
| P value | .49 | .28 | .78 | .24 |
| WLZ† | ||||
| Beta | 0.39 | 1.25 | 0.28 | 0.70 |
| 95% CI | −0.97 to 1.76 | −0.48 to 2.97 | −0.52 to 1.09 | −0.45 to 1.85 |
| P value | .57 | .16 | .49 | .23 |
| Anthropometry in midchildhood (4-9 years) | ||||
| HAZ | ||||
| Beta | −0.21 | −0.06 | −0.51 | −0.39 |
| 95% CI | −1.86 to 1.44 | −1.84 to 1.71 | −1.59 to 0.58 | −1.57 to 0.79 |
| P value | .80 | .94 | .36 | .51 |
| BMIZ | ||||
| Beta | 1.54 | 2.21 | 0.42 | 0.85 |
| 95% CI | −0.26 to 3.35 | 0.40 to 4.02 | −0.78 to 1.62 | −0.39 to 2.08 |
| P value | .09 | .02 | .49 | .18 |
Multivariate models for systolic and diastolic blood pressure control for which trial the child participated in, treatment arm, child's sex, gestational age at birth, and age at mid-childhood follow-up. Multivariate models diastolic blood pressure adjust for which trial the child originally participated in, whether the child was randomized to multivitamin supplementation, maternal height (cm), child's gestational age at birth, and child's age at follow-up visit.
Multivariate models with anthropometric indicators as predictors also include the corresponding anthropometric indicator at 6 weeks of age or change from 6 to 52 weeks of age, for example, the model reporting the beta parameter for LAZ at 6 weeks adjusts for change in LAZ from 6 to 52 weeks of age, and vice versa.
n = 66 (children from second trial only).