Figure 1. Antigen availability promotes maintenance of CD4 T cells during Mtb infection.
(A) CFSE dilution in adoptively transferred transgenic T cells isolated from the lung 5 days after transfer.
(B) Enumeration of Ag85B and ESAT-6-specific tetramer+ CD4 T cells in the lung. Data are representative of 2 independent experiments with 3–5 mice per group and per time point.
(C) Enumeration of IFN-γ-producing Ag85B or ESAT-6-specific T cells in latently infected adolescents. The p-value was calculated using the Wilcoxon signed-rank test. See also Figure S1.