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. Author manuscript; available in PMC: 2018 Jun 14.
Published in final edited form as: Cell Host Microbe. 2017 Jun 14;21(6):695–706.e5. doi: 10.1016/j.chom.2017.05.012

Figure 2. Chronic antigenic stimulation drives murine Mtb-specific CD4 T cells towards terminal differentiation.

Figure 2

(A) PD1 and KLRG1 expression on Ag85B and ESAT-6-specific CD4 T cells in the lung. The percentage of KLRG1+ cells is shown.

(B) CD62L, CCR7 and IL-7Rα expression on lung naïve, Ag85B-specific, or ESAT-6-specific CD4 T cells at 103 days post-infection. Graphs depict the mean fluorescence intensity (MFI) for individual mice. See also Figure S3.