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. Author manuscript; available in PMC: 2018 Jun 29.
Published in final edited form as: Cell. 2017 Jun 29;170(1):158–171.e8. doi: 10.1016/j.cell.2017.06.018

Figure 2. mcr functions in an additive manner with caspases during salivary gland degradation.

Figure 2

(A) Animals with salivary gland-specific p35 expression (n = 16), mcr knockdown (n = 24), and p35 expression plus mcr knockdown (n = 25) analyzed by histology for the presence of salivary gland material at 24h after puparium formation. Yellow circles, cell fragments; red circle, salivary gland fragments.

(B) Quantification of data from (A). Statistical significance: Chi-square test.

(C and D) Salivary glands dissected 6h (C) and 14h after puparium formation (D) from control animals and those with salivary gland-specific mcr knockdown, stained with anti-cleaved Lamin antibody (green) and Hoechst (blue). Scale bars, 50 µm.

(E) Quantification of data from (C and D). Error bars, mean ± SEM; n = 12 (control 6h), n = 10 (control 14h), n = 10 (mcrIR 6h), n = 14 (mcrIR 6h). Statistical significance: Student’s t-test.

See also Figure S2.