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. Author manuscript; available in PMC: 2018 Jan 27.
Published in final edited form as: N Engl J Med. 2017 Jun 3;377(4):338–351. doi: 10.1056/NEJMoa1702900

Figure 2. Forest Plots of Treatment Effect on Overall and Failure-free Survival within Subgroups According to Stratification Factors at Randomization.

Figure 2

In each panel, the dashed vertical line is the point estimate of the hazard ratio for the analysis. Gleason scores range from 3 to 10, with higher scores indicating more aggressive disease, less differentiated tumor, and worse prognosis. The World Health Organization (WHO) performance status was scored on a scale of 0 to 4, with higher numbers indicating greater disability. Time period was defined by corecruiting group; ABCEG corresponds to November 2011 through January 2013, ABCEGH January 2013 through March 2013, and AGH April 2013 through January 2014. NSAID denotes nonsteroidal antiinflammatory drug.