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. 2017 Apr 5;28(8):2364–2376. doi: 10.1681/ASN.2016060694

Figure 3.

Figure 3.

RA increases NRIP1 binding to RARα in vitro. (A) Coimmunoprecipitation of protein lysates of wild type (WT) NRIP1 and RARα overexpressed in HEK293 cells. Note that the Trp93fs* mutation abrogates binding to RARα. Treatment with RA increases WT NRIP1 binding to RARα (orange boxes). (B) Quantification of data shown in (A). RARα coimmunoprecipitation band intensity was normalized to WT NRIP1 immunoprecipitation band intensity in the absence and presence of RA. *P<0.05, average of three separate experiments.