Table 3.
Multivariate Cox regression model of the risk of death associated with cumulative (1 year) exposure to FO across systolic BP categories
| Variables | HR (95% CI) |
|---|---|
| BP<130 FO normal | 1.19 (1.06 to 1.33) |
| BP<130 FO high | 1.94 (1.68 to 2.23) |
| BP=130–160, FO normal | 1.00 (Reference) |
| BP=130–160, FO high | 1.51 (1.35 to 1.69) |
| BP>160, FO normal | 1.18 (1.00 to 1.38) |
| BP>160, FO high | 1.62 (1.39 to 1.90) |
| Sex (1= man) | 1.09 (0.98 to 1.21) |
| Age, per yr | 1.03 (1.03 to 1.04) |
| Height, per cm | 1.00 (0.99 to 1.00) |
| Weight predialysis, per kg | 0.99 (0.99 to 1.00) |
| Preweight − postweight, per kg | 1.05 (0.98 to 1.12) |
| BMI, per kg/m2 | 1.00 (0.99 to 1.01) |
| Treatment time, per min | 1.00 (1.00 to 1.00) |
| Smoking (1= yes) | 1.09 (0.99 to 1.20) |
| Ethnicity (1= white) | 0.82 (0.72 to 0.94) |
| Diabetes | 1.13 (1.03 to 1.23) |
| Coronary artery disease | 1.63 (1.46 to 1.82) |
| Congestive heart failure | 1.66 (1.52 to 1.81) |
| Peripheral vascular disease | 0.99 (0.90 to 1.09) |
| Dementia | 1.26 (0.96 to 1.65) |
| Chronic bronchopulmonary disease | 1.16 (1.03 to 1.31) |
| Paraplegia | 0.83 (0.46 to 1.50) |
| Liver disease | 1.01 (0.88 to 1.16) |
| Connective tissue disorder | 1.16 (0.82 to 1.63) |
| Cerebrovascular disease | 1.11 (0.98 to 1.25) |
| Hb, per g/L | 0.98 (0.98 to 0.99) |
| Albumin, per g/L | 0.93 (0.92 to 0.94) |
| Na, per mmol/L | 0.97 (0.95 to 0.98) |
| Phosphate, per mg/dl | 1.03 (0.99 to 1.07) |
| LDL, per mg/dl | 1.00 (1.00 to 1.00) |
| HDL, per mg/dl | 1.00 (1.00 to 1.00) |
| CRP, per mg/L | 1.04 (1.03 to 1.06) |
| PCRn, per g/kg per d | 0.81 (0.73 to 0.89) |
| Kt/V | 0.97 (0.96 to 0.98) |
| Use of AHT medication (1= yes) | 1.13 (1.03 to 1.23) |
In this analysis, systolic BP, predialysis weight, and postdialysis weight (and the difference between predialysis weight and postdialysis weight) of the days on which fluid volume (BMC) was measured were averaged and taken as study variables for the multivariate Cox regression. All comorbidities: 1= yes. BMI, body mass index; Hb, hemoglobin; Na, sodium; CRP, C-reactive protein; PCRn, normalized protein catabolic rate; AHT, antihypertensive treatment.