Table 3. Simulation results of cluster model 2 (20%, 30%, and 40% of the total cases in the true cluster of irregular shape).
Maximum reported cluster size | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5 | 6 | 8 | 10 | 12 | 15 | 20 | 25 | 30 | 35 | 40 | 45 | 50 | Default | |
Circular shape | ||||||||||||||
2000 cases | ||||||||||||||
# of OMRCS | 28 | 554 | 291 | 10 | 9 | 98 | 0 | 0 | 10 | 0 | 0 | 0 | 0 | |
Sensitivity | 1.00 | 1.00 | 1.00 | 0.98 | 1.00 | 1.00 | - | - | 1.00 | - | - | - | - | 0.99 |
PPV | 1.00 | 1.00 | 1.00 | 0.77 | 0.78 | 1.00 | - | - | 0.71 | - | - | - | - | 0.74 |
3000 cases | ||||||||||||||
# of OMRCS | 556 | 27 | 317 | 8 | 92 | 0 | 0 | 0 | 0 | 0 | 0 | |||
Sensitivity | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | - | - | - | - | - | - | 0.99 | ||
PPV | 1.00 | 1.00 | 1.00 | 0.5 | 1.00 | - | - | - | - | - | - | 0.72 | ||
4000 cases | ||||||||||||||
# of OMRCS | 0 | 0 | 0 | 29 | 536 | 231 | 101 | 57 | 36 | 0 | 0 | 0 | 0 | |
Sensitivity | - | - | - | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | - | - | - | - | 1.00 |
PPV | - | - | - | 1.00 | 1.00 | 1.00 | 0.99 | 0.99 | 1.00 | - | - | - | - | 0.71 |
Elliptic shape | ||||||||||||||
2000 cases | ||||||||||||||
# of OMRCS | 37 | 672 | 104 | 35 | 5 | 102 | 40 | 5 | 0 | 0 | 0 | 0 | 0 | |
Sensitivity | 0.99 | 0.99 | 1.00 | 0.98 | 0.92 | 0.99 | 1.00 | 1.00 | - | - | - | - | - | 0.97 |
PPV | 1.00 | 1.00 | 0.92 | 0.85 | 1.00 | 0.87 | 1.00 | 0.83 | - | - | - | - | - | 0.99 |
3000 cases | ||||||||||||||
# of OMRCS | 0 | 0 | 663 | 32 | 105 | 14 | 123 | 11 | 46 | 6 | 0 | 0 | 0 | |
Sensitivity | - | - | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.99 | 1.00 | - | - | - | 0.99 |
PPV | - | - | 1.00 | 1.00 | 0.86 | 0.78 | 0.96 | 0.78 | 1.00 | 0.83 | - | - | - | 0.99 |
4000 cases | ||||||||||||||
# of OMRCS | 0 | 0 | 0 | 33 | 557 | 217 | 16 | 73 | 32 | 0 | 69 | 3 | 0 | |
Sensitivity | - | - | - | 1.00 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | - | 1.00 | 1.00 | - | 1.00 |
PPV | - | - | - | 1.00 | 1.00 | 0.98 | 0.85 | 0.96 | 0.81 | - | 1.00 | 0.83 | - | 0.97 |
# of OMRCS, frequency chosen as the optimal maximum reported cluster size by the Gini coefficient among 1000 random data sets; PPV, positive predictive value.