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. 2017 Jul 17;11(4):044104. doi: 10.1063/1.4991738

FIG. 2.

FIG. 2.

Human umbilical vein endothelial cells (HUVEC) inflammatory and pro-EndMT gene expression. (a) Vascular endothelial-cadherin (VE-cadherin; CDH5), (b) pro-inflammatory cell receptor intercellular adhesion molecule-1 (ICAM-1), and (c) vascular cell adhesion molecule-1 (VCAM-1). (d) Endothelial to mesenchymal transformation (EndMT) markers, actin, alpha 2 (ACTA2) and (e) Snail. Error bars show mean ± SEM, n = 3 culture wells. All static or all fluidic conditions were analyzed with a one-way ANOVA with Tukey's post-test. Tukey groups are shown for statistically significant results (p < 0.05). Identical extracellular matrix conditions exposed to static or shear conditions were analyzed with an unpaired Student's t-test. Bars connected with * represent statistical significance with an unpaired Student's t-test (p < 0.05).