Table 3. Costa Rica: Absolute and relative distribution of response by the line of treatment, by the type of treatment and stage of disease. Patients with retinoblastoma—HNN, 2009–2015.
| Response to the first line of treatment | Type of treatment | Stage | Cases | Percentage |
|---|---|---|---|---|
| Stable disease | Conservative | A–C | 4 | 8.8 |
| D–E | 1 | 2.2 | ||
| Progressive disease | Aggressive | A–C | 0 | 0 |
| D–E | 1 | 2.2 | ||
| Conservative | A–C | 7 | 15.5 | |
| D–E | 5 | 11.1 | ||
| Complete response1/ | Aggressive | A–C | 1 | 2.2 |
| D–E | 26 | 57.7 | ||
| Subtotal | 45 | 100.0 | ||
| Response to the second line of treatment | Type of treatment | Stage | Cases | Percentage |
| Stable disease | Conservative | A–C | 1 | 8.3 |
| D–E | 1 | 8.3 | ||
| Progressive disease | Conservative | A–C | 2 | 16.6 |
| D–E | 6 | 50.0 | ||
| Complete response | Aggressive | A–C | 1 | 8.3 |
| D–E | 1 | 8.3 | ||
| Subtotal | 12 | 100.0 | ||
| Response to the third line of treatment | Type of treatment | Stage | Cases | Percentage |
| Stable disease | Conservative | A–C | 1 | 12.5 |
| Progressive disease | Aggressive | D–E | 1 | 12.5 |
| Conservative | A–C | 1 | 12.5 | |
| D–E | 2 | 25.0 | ||
| Complete response | D–E | 3 | 37.5 | |
| Subtotal | 8 | 100.0 | ||
| Response to the fourth line of treatment | Type of treatment | Stage | Cases | Percentage |
| Stable disease | Conservative | D–E | 1 | 33.3 |
| Complete response | Aggressive | D–E | 2 | 66.7 |
| Subtotal | 3 | 100.0 | ||
Source: patient records, HNN.