Table 2.
Summary of tuned targets
| Patient ID | BP-clinic (mmHg) | BP-sim (mmHg) | SV-clinic (ml/cycle) | SV-sim (ml/cycle) | %CO to Cor-lit | %CO to Cor-sim | L-R flow-sim in % |
|---|---|---|---|---|---|---|---|
| Patient 1 | 124/73 | 118/74.5 | 60.9 | 63.5 | 4.0 | 4.0 | 65.7–34.3 |
| Patient 2 | 133/85 | 133/85.5 | 80.4 | 84.7 | 4.0 | 3.9 | 82.0–18.0 |
| Patient 3 | 135/78 | 133/78 | 78.1a | 75.8 | 4.0 | 4.0 | 52.5–47.5 |
| Patient 4 | 115/74 | 117/74 | 115.1 | 114.8 | 4.0 | 4.1 | 56.4–43.6 |
| Patient 5 | 113/69 | 115/68 | 70.5 | 70.6 | 4.0 | 4.1 | 74.0–26.0 |
Summary of non-invasive clinical measurements, population averaged targets from literature and respective quantities from simulations. The LPN was tuned to match, within 10 % error, a combination of non-invasive clinical measurements for the patient and population averaged values from literature
BP blood pressure (mmHg), SV stroke volume (ml/cardiac cycle), % CO to Cor percentage of cardiac output perfusing the coronaries, L-R left-right coronary flow expressed in percentage, -clinic value from clinic, -sim value from simulation, -lit value from literature
a
No echocardiogram data for patient, body mass index-based population average was used