Table 1.
Patient Demographics for all 30 patients in the study,
| Control | Partial IC | Complete IC | P value | |||
|---|---|---|---|---|---|---|
|
| ||||||
| Age, Yrs (mean ± SD) | 62±6.8 | 65±4.8 | 64±9.7 | 0.801 | ||
|
| ||||||
| Gender (M:F) | 9:0 | 8:0 | 10:03 | 0.172 | ||
|
| ||||||
| BMI, (mean ± SD) | 31±5.8 | 27±4.8 | 26±4.0 | 0.091 | ||
|
| ||||||
| ASA class, No.(%) | 0.012 | |||||
| 1–2 | 0 | 0 | 6(46) | |||
| 3–4 | 9(100) | 8(100) | 7(54) | |||
|
| ||||||
| Indications for IC, No. (%) | ||||||
| Planned Laparoscopy | - | 8(100) | 8(62) | 0.112 | ||
| High-Risk Ischemia | 0 | 5(38) | ||||
|
| ||||||
| Clinical Stage, No. (%) | 0.022 | |||||
| I | 4(44) | 1(13) | 0 | |||
| II | 1(11) | 0 | 5(38) | |||
| III | 4(44) | 7(88) | 8(62) | |||
|
| ||||||
| Pathologic Stage, No. (%) | 0.512 | |||||
| (Pathologic Complete Response) 0 | 2(22) | 2(25) | 4(31) | |||
| I | 2(22) | 0 | 1(8) | |||
| II | 2(22) | 3(38) | 3(23) | |||
| III | 3(33) | 3(38) | 5(38) | |||
|
| ||||||
| Neoadjuvant Therapy, No. (%) | 0.022 | |||||
| Yes | 5(56) | 7(88) | 13(100) | |||
| No | 4(44) | 1(8) | 0 | |||
|
| ||||||
| Cancer Histology, No.(%) | 0.962 | |||||
| Adenocarcinoma | 8(89) | 7(88) | 11(85) | |||
| Squamous Cell | 1(9) | 1(13) | 2(15) | |||
|
| ||||||
| Comorbidities, No.(%) | ||||||
|
| ||||||
| Current Tobacco Use | 0 | 3(38) | 4(31) | 0.142 | ||
|
| ||||||
| Former Tobacco Use | 8(89) | 5(63) | 7(54) | 0.232 | ||
|
| ||||||
| Cardiac Arrhythmia | 0 | 0 | 2(15) | 0.502 | ||
|
| ||||||
| DM | 3(33) | 1(13) | 2(15) | 0.262 | ||
|
| ||||||
| CAD | 2(22) | 1(13) | 3(23) | 0.652 | ||
|
| ||||||
| CHF | 1(11) | 0 | 1(8) | 0.832 | ||
|
| ||||||
| PVD | 1(11) | 1(13) | 4(31) | 0.452 | ||
|
| ||||||
| CKD | 0 | 0 | 1(8) | 0.522 | ||
|
| ||||||
| Pulmonary Disease | 2(22) | 0 | 3(23) | 0.352 | ||
|
| ||||||
| Liver Disease | 0 | 1(13) | 0 | 0.252 | ||
IC, Ischemic Conditioning; BMI, body mass index; ASA, American Society of Anesthesiologists; DM, Diabetes Mellitus; CAD, Coronary Artery Disease; CHF, Congestive Heart Failure; PVD, Peripheral Vascular Disease; CKD, Chronic Kidney Disease
1
One way Analysis of Variance,
2
Fisher’s Exact Test