Skip to main content
. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Epidemics. 2017 Feb 21;19:74–82. doi: 10.1016/j.epidem.2017.02.008

Table 2.

Parameters in the transmission process

Parameter Meaning Value/Source
θ Cross-immunity: reduction in the susceptibility to one strain following natural infection with another strain 90%; 70%; 50%
V Vaccine valency “Bivalent”; “Monovalent”
L Vaccine coverage levels in the 5 age groups 40% children, 30% adults (baseline scenario); (37%,27%); (30%,22.7%); (24%,18%) (alternative)
ni Population size, age group i. Age groups are (0–4,5–17,18–49,50–64,65+) [28]
cij Contact rate between age groups i and j [26]
sik
Susceptibility to strain k in age group i Drawn uniformly between [0.75,1] for age groups 1–3; 0.65 for age group 4; 0.4 for age group 5
w() Serial interval distribution [29]
λ Scaling parameter for transmission (eq. 1) See description following eq. 1
D Delay (in days) between the introduction of the first infected individuals for strain 2 vs. 1 Drawn uniformly between [−35,35]
E Vaccine efficacies against the two strains for the monovalent and the bivalent vaccines Vaccine-type strain: 40%/non-elderly, 30%/elderly. Non-vaccine strain: 40%/non-elderly, 30%/elderly (bivalent vaccine); Drawn uniformly between [0,20%]/non-elderly, [0,15%]/elderly (monovalent vaccine)