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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Gastroenterology. 2017 Feb 7;152(6):1329–1336.e1. doi: 10.1053/j.gastro.2017.02.002

Table 3.

Adjusted Survival Analysis of Time to Progression for Celiac Disease Autoimmunity (CDA) and Celiac Disease (CD). Acceleration factor summarizes the relative time to event compared to a reference group.

Celiac Disease Autoimmunity Celiac Disease
Parameter Acceleration
Factor
95% CI P value Acceleration
Factor
95% CI P value
Sex Female 0.83 0.66 – 1.04 0.11 Female 0.65 0.42 – 1.01 0.06
Male reference group Male reference group
HLA genotype DR3-DQ2/DR3-DQ2/ 0.42 0.25 – 0.73 0.002 DR3-DQ2/DR3-DQ2/ 0.14 0.06–0.33 <0.0001
DR3-DQ2/DR4-DQ8 0.60 0.42 – 0.86 0.006 DR3-DQ2/DR4-DQ8 0.24 0.12 – 0.48 <0.0001
DR3-DQ2/X 0.61 0.41 – 0.91 0.01 DR3-DQ2/X 0.21 0.10 – 0.44 <0.0001
DR4-DQ8/DR4-DQ8 0.81 0.50 – 1.31 0.39 DR4-DQ8/DR4-DQ8 0.40 0.16 – 1.00 0.05
DR4-DQ8/X reference group DR4-DQ8/X reference group
First-degree relative with CD yes 0.64 0.31 1.32 0.23 Yes 0.13 0.05 – 0.36 <0.0001
no reference group no reference group

CI – confidence interval