Table 3.
Celiac Disease Autoimmunity | Celiac Disease | |||||||
---|---|---|---|---|---|---|---|---|
Parameter | Acceleration Factor |
95% CI | P value | Acceleration Factor |
95% CI | P value | ||
Sex | Female | 0.83 | 0.66 – 1.04 | 0.11 | Female | 0.65 | 0.42 – 1.01 | 0.06 |
Male | reference group | Male | reference group | |||||
HLA genotype | DR3-DQ2/DR3-DQ2/ | 0.42 | 0.25 – 0.73 | 0.002 | DR3-DQ2/DR3-DQ2/ | 0.14 | 0.06–0.33 | <0.0001 |
DR3-DQ2/DR4-DQ8 | 0.60 | 0.42 – 0.86 | 0.006 | DR3-DQ2/DR4-DQ8 | 0.24 | 0.12 – 0.48 | <0.0001 | |
DR3-DQ2/X | 0.61 | 0.41 – 0.91 | 0.01 | DR3-DQ2/X | 0.21 | 0.10 – 0.44 | <0.0001 | |
DR4-DQ8/DR4-DQ8 | 0.81 | 0.50 – 1.31 | 0.39 | DR4-DQ8/DR4-DQ8 | 0.40 | 0.16 – 1.00 | 0.05 | |
DR4-DQ8/X | reference group | DR4-DQ8/X | reference group | |||||
First-degree relative with CD | yes | 0.64 | 0.31 1.32 | 0.23 | Yes | 0.13 | 0.05 – 0.36 | <0.0001 |
no | reference group | no | reference group |
CI – confidence interval