Table 3. Distribution of phthalate metabolites (ng/mL) in spot urine in child (n=229) and prenatal sample (n=181) *.
| Child Sample | Prenatal Sample | |||||
|---|---|---|---|---|---|---|
| Metabolite | % > LODa | Geometric Meanb (95% CI) | Range | % > LODa | Geometric Meanb (95% CI) | Range |
| MEHP | 83.0 | 3.2 (2.8, 3.7) | <LOD to 47 | 86.7 | 5.7 (4.7, 6.9) | <LOD to 213 |
| MEHHP | 99.6 | 32.8 (27.9, 38.5) | <LOD to 646 | 100 | 23.6 (19.6, 28.5) | 1.1 – 1380 |
| MnBP | 100 | 41.9 (35.8, 48.9) | 1.9 – 2020 | 100 | 37.8 (32.2, 44.5) | 1.2 – 1110 |
| MBzP | 100 | 23.0 (18.8, 28.3) | 0.3 – 2254 | 99.4 | 15.3 (12.4, 18.8) | <LOD to 550 |
| MiBP | 99.6 | 10.3 (8.7, 12.1) | <LOD to 260 | 98.9 | 8.3 (7.1, 9.6) | <LOD to 89 |
| MEP | 100 | 138.6 (116.8, 164.6) | 8.0 – 5848 | 100 | 161.8 (135.6, 193.0) | 7.9 – 3986 |
| MEOHP | 99.6 | 19.2 (16.4, 22.5) | <LOD to 345 | 100 | 19.7 (16.4, 23.7) | 0.9 – 795 |
| MECPP | 100 | 61.0 (52.9, 70.3) | 1.2– 933 | 100 | 41.6 (35.2, 49.2) | 3.2 – 1210 |
*
Concentrations are not adjusted for specific gravity.
a
Limit of detection (LOD) was 0.25–1.2 ng/mL for MEHP, 0.35– 0.7 for MEHHP; and 0.10– 0.30 ng/mL for MiBP, 0.35–0.7 ng/mL for MEOHP.
b
Used imputed values to calculate geometric mean
MEHP=mono(2-ethylhexyl) phthalate, MEHHP=mono(2-ethyl-5-hydroxyhexyl) phthalate, MnBP=mono-n-butyl phthalate, MBzP=monobenzyl phthalate, MiBP=mono-isobutyl phthalate, MEP=monoethyl phthalate, MEOHP=mono(2-ethyl-5-oxohexyl) phthalate, MECPP=mono(2-ethyl-5-carboxypentyl) phthalate,