. Author manuscript; available in PMC: 2018 Aug 1.

Published in final edited form as: J Nerv Ment Dis. 2017 Aug;205(8):634–640. doi: 10.1097/NMD.0000000000000669

Table 3.

Association between change in depressive symptoms and clinically significant fitness and weight loss outcomes from baseline to 12-months

Clinically significant outcomes	β	95% CI	p^a
Fitness (>50 meter increase on the 6-MWT)^b	−4.39	−8.35 to −0.44	0.030
Weight loss (≥5%)	−2.58	−5.72 to 0.55	0.106
Weight loss (≥10%)	−4.38	−8.65 to −0.12	0.044
Cardiovascular risk reduction (≥5% or >50 meter increase on the 6-MWT)	−3.41	−6.45 to −0.37	0.028

P-values from linear regression models controlling for treatment group, study (RCT 1 or RCT 2), age, gender, mental health diagnosis, race, and use of antidepressant.

Fitness was measured using the 6-Minute Walk Test (6-MWT), which measures the number of meters that an individual can walk in 6 minutes. Higher values indicate better fitness.