Table 2.
Summary of Hardy–Weinberg Equilibrium test and allelic and genotypic frequencies genotypes for CXCL9-11 polymorphisms in HCV-infected patients compared to Iberian population (data from HapMap) (http://browser.1000genomes.org/index.html)
| SNPs | HCV cohort (n = 389) | IBS group (n = 107) | χ2 testa | χ2 testb | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HWE | Alleles | Genotype | HWE | Alleles | Genotype | p value | p value | |||||
| CXCL9 rs10336 | 0.738 | A | 41% | AA | 16% | 0.677 | A | 45% | AA | 22% | 0.568 | 0.556 |
| G | 59% | AG | 50% | G | 55% | AG | 46% | |||||
| GG | 34% | GG | 32% | |||||||||
| CXCL10 rs3921 | 0.841 | C | 41% | CC | 16% | 0.884 | C | 45% | CC | 21% | 0.568 | 0.653 |
| G | 59% | CG | 49% | G | 55% | CG | 47% | |||||
| GG | 35% | GG | 32% | |||||||||
| CXCL11 rs4619915 | 0.841 | A | 41% | AA | 16% | 0.884 | A | 44% | AA | 21% | 0.668 | 0.650 |
| G | 59% | AG | 49% | G | 56% | AG | 45% | |||||
| GG | 35% | GG | 34% | |||||||||
Statistical: p values were calculated by Chi squared test
HWE Hardy–Weinberg Equilibrium, HCV hepatitis C virus, IBS Iberian populations in Spain, CXCL chemokine (C-X-C motif) ligand
aDifferences between allele frequencies
bDifferences between genotype frequencies