Table 6.
Association between CXCL9-11 haplotypes and liver fibrosis stage in HCV-infected patients
| CXCL9-11 Haplotypes | Association | p | ||||
|---|---|---|---|---|---|---|
| rs10336 | rs3921 | rs4619915 | Freq. | aOR (95% CI) | ||
| F ≥ 2 (≥7.1 kPa) | G | G | G | 0.581 | 0.95 (0.70; 1.30) | 0.760 |
| A | C | A | 0.401 | 1.01 (0.74;1.39) | 0.929 | |
| A | G | G | 0.011 | 2.50 (0.59;10.5) | 0.198 | |
| F ≥ 3 (≥9.5 kPa) | G | G | G | 0.581 | 0.97 (0.70;1.36) | 0.868 |
| A | C | A | 0.401 | 1.10 (0.78;1.54) | 0.597 | |
| A | G | G | 0.011 | 0.32 (0.04;2.64) | 0.226 | |
| F4 (≥12.5 kPa) | G | G | G | 0.581 | 0.91 (0.62;1.34) | 0.629 |
| A | C | A | 0.401 | 1.12 (0.76;1.66) | 0.557 | |
| A | G | G | 0.011 | 0.58 (0.07;4.85) | 0.591 | |
Statistical: p values were calculated by multivariate logistic regression adjusted by the most important clinical and epidemiological characteristics
95% CI 95% of confidence interval, aOR adjusted odds ratio, p value level of significance, F ≥ 2 significant fibrosis, F ≥ 3 advance fibrosis, F4 cirrhosis, HCV-GT hepatitis C virus genotype, CXCL chemokine (C-X-C motif) ligand