Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jul 28;7:6829. doi: 10.1038/s41598-017-05748-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Ankyrin repeat overview and TANC1 Ankyrin domain model. (A) Consensus sequence of TANC ankyrin modules and related sequence logo. Residues that match the published consensus⁵⁷ are reported in upper case. Secondary structure is shown above the alignment: the inner alpha helix (α1) and the outer alpha helix (α2) are connected by a turn-loop (black line). (B) Graphic representation of ANK repeats structure in TANC proteins. Conserved positions of ankyrin consensus pattern are reported in the diagram as spheres. Colour code refers to consensus logo: hydrophobic amino acids (A, L and V) are in light blue, glycine in orange, threonine and asparagine in green, histidine in teal, glutamate in violet, and proline in yellow. Residues matching the published consensus⁵⁷ are reported in bold. (C) Cartoon of TANC1 AR domain model is coloured from N-terminus (blue) to C-terminus (red). Electrostatic properties of turn-loop surfaces and connecting-loop surfaces are shown: negative charges in blue and red charges in red. Consurf analysis of turn-loop surface and connecting-loop surface, colour code from unconserved (cyan) to conserved (purple) residues.