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. 2017 Jul 28;7:6794. doi: 10.1038/s41598-017-06354-1

Figure 9.

Figure 9

Schematic to show the balance between polymer degradation and cell growth: (a) in the first stage, surface hydrophilicity and chemical groups of polymeric substrates play key roles to promote cell adhesion, spread and proliferation; (b) in the second stage, the polymeric substrates begin to degrade, affecting the interfacial pH and the secretions from cells, which contribute to the enhanced effect on osteogenic differentiation of osteoblasts.