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. 2017 Jul 28;7:6827. doi: 10.1038/s41598-017-07189-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Enrichment of nodes degree in each percentile level for genes in the integrated diagnostic network. The percentile levels were defined as <25, 25–50, 50–75, and >75 percentile of the degrees of each gene in the integrated diagnostic network, which correspond to 1–27, 28–52, 53–111, and >111 number of degrees, respectively. ‘Genes_BioGRID’ represents the number of genes from BioGRID felt into a given percentile level of node degree, and ‘Genes_Selected’ shows that from the integrated diagnostic network.