Table 2.

Synthetic biology bibliometric keyword review

Search	Keywords	Noise ratio	Origin	Specific exclusion terms
1	“synthetic *nucleotide”	0	VD	“photosynthe*”
2	“artificial nucleic acid*”	0	VD	None
3	“artificial gene* network”	0	VD	“gener*”
4	“artificial *nucleotide”	0	VD	None
5	“artificial gene* circuit*” AND “biological system”	0	New	“gener*”
6	“artificial cell”	0	VD	“cell* telephone” OR “cell* phone” OR “cell* culture” OR “logic cell*” or “fuel cell*” or “battery cell*” or “load-cell*” or “geo-synthetic cell*” or “memory cell*” or “cellular network” or “ram cell*” or “rom cell*” or “maximum cell*” OR “electrochemical cell*” OR “solar cell*”
7	“synthetic biolog*”	0.001417	Comm.	“photosynthe*”
8	“synthetic dna”	0	New	“photosynthe*”
9	“synthetic genom*”	0	VD/OD	“photosynthe*”
10	“synthetic gene*”	0	VD	“synthetic gener*” OR photosynthe*”
11	“synthetic cell”	0	VD/New	“cell* telephone” OR “cell* phone” OR “cell* culture” OR “logic cell*” or “fuel cell*” or “battery cell*” or “load-cell*” or “geo-synthetic cell*” or “memory cell*” or “cellular network” or “ram cell*” or “rom cell*” or “maximum cell*” OR “electrochemical cell*” OR “solar cell*” OR “photosynthe*”
12	“synthetic promoter”	0	New	“photosynthe*”
13	“synthetic gene* cluster”	0	VD	“photosynthe*”
14	“synthetic mammalian gene*” AND “mammalian cell”	0	New	“photosynthe*”
15	(“bio brick” or “biobrick” or “bio-brick”)	0	Expert	None

See text for discussion of noise ratio comparison of benchmark and random publications

VD = suggested by van Doren et al. (2013), OD = suggested by Oldham et al. (2012), New = newly added keywords, Expert = suggested by expert, Comm. = common keywords shared by VD, OD, and New