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. 2016 Oct 3;18(7):847–858. doi: 10.1007/s10198-016-0830-1

Table 2.

Unadjusted mean social annual cost data per patient by cost component and by CKD stages 4 and 5 pre-dialyses (Euro 2016)

Cost component CKD stage 4 CKD stage 5 Overall p a
Mean SD % Mean SD % Mean SD %
Direct medical cost
Laboratory test 281.5 ±222.6 3.8 392.6 ±233.2 4.4 328.5 ±233.4 4.1
Specialist visit 101.6 ±69.9 1.4 126.3 ±66.6 1.4 112.1 ±69.5 1.4
Diagnostic exam 157.4 ±167.4 2.1 186.0 ±176.0 2.1 169.5 ±171.5 2.1
Hospitalization 1362.4 ±3250.6 18.4 1895.6 ±3100.4 21.1 1588.2 ±3195.5 19.7
Drugs 2075.1 ±2016.3 28.0 2629.3 ±2173.7 29.3 2309.8 ±2100.2 28.6
Total 3978.1 ±4187.0 53.6 5229.8 ±4161.2 58.3 4508.2 ±4217.5 55.8 0.001
Direct non-medical cost
Out-of-pocket cost of diet 154.7 ±421.9 2.1 170.4 ±420.7 1.9 161.3 ±421.1 2.0
Reimbursement of diet 447.8 ±285.4 6.0 539.0 ±207.1 6.0 486.4 ±258.9 6.0
Transport of patient and caregiver 60.4 ±80.4 0.8 75.5 ±84.5 0.8 66.8 ±82.4 0.8
Paid domestic help 701.7 ±2378.0 9.5 508.3 ±2208.6 5.7 619.8 ±2307.4 7.7
Informal care 1705.6 ±3516.0 23.0 1651.1 ±3458.1 18.4 1682.5 ±3488.1 20.8
Total 3070.2 ±3984.9 41.4 2944.3 ±3958.0 32.8 3016.9 ±3969.9 37.3 0.731
Indirect costs
Loss of productivity of patient and caregivers 373.4 ±2142.6 5.0 796.7 ±3297.0 8.9 552.7 ±2697.6 6.8 0.109
Overall 7421.6 ±6255.2 100.0 8971.0 ±6503.3 100.0 8077.8 ±6400.9 100.0 0.008

CKD chronic kidney disease, SD standard deviation

aTwo-sample t test