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. 2017 Jul 27;91(16):e00525-17. doi: 10.1128/JVI.00525-17

TABLE 2.

Viral loads after DENV2 challenge

Group Monkey DENV2 load (RNA copies/ml) on postchallenge daya:
2 3 4 5 6 10
Vaccinated r09084 <20 <20 <20 <20 <20 <20
r10019 <400 <400 <400 1,120 <400 3,360
r12078 <20 <20 <20 <20 <20 ND
rhBE94 15,900 17,700 33,300 88,400 18,200 <20
Control rh2313 1,560 760 730 3,230 14,300 28,600
r08037 520 610 <400 <400 4,410 5,950,000
a

Viral loads were quantified via quantitative real-time PCR. Monkeys were challenged 19 weeks after inoculation of recombinant RRV. <20 indicates that the viral load was below the limit of detection of 20 DENV2 RNA copies/ml plasma; <400 indicates that the monkeys tested positive but that the viral load was below the limit of quantitation; ND, not done.