TABLE 1.

Forward and all-subsets regression for model selection for viral load

FARMS target	Estimate	SE	t value	Pr(>|t|)	Significancea
Intercept	−7.73E+01	2.51E+02	−0.308	0.759395
ACVR2A	−7.76E−02	5.97E−03	−12.997	<2.E−16	***
BMP2	−6.18E−01	3.59E−02	−17.230	<2.E−16	***
BMP3	1.26E−01	1.78E−02	7.116	2.93E−09	***
CCL13_hu	4.51E−02	3.75E−03	12.022	<2.E−16	***
CCL13_X	−8.38E−02	2.89E−02	−2.906	0.005339	**
CCL20	1.81E−02	5.28E−03	3.434	0.001163	**
CCL21	1.88E−02	9.03E−03	2.079	0.042505	*
CLEC11A	−6.96E−02	4.56E−03	−15.239	<2.E−16	***
CNTNAP1	−5.49E−01	2.84E−02	−19.322	<2.E−16	***
COL18A1	−3.39E−01	2.65E−02	−12.816	<2.E−16	***
CSF1	−1.11E−02	3.56E−03	−3.133	0.002820	**
CST3	−1.07E−02	3.47E−03	−3.079	0.003287	**
CTF1	−3.50E−02	8.50E−03	−4.111	0.000138	***
CXCL16	5.31E−01	3.73E−02	14.218	<2.E−16	***
FGF17	4.23E−02	4.06E−03	10.421	1.95E−14	***
FGF3_hu	2.22E−01	4.81E−02	4.617	2.52E−05	***
FTL_hu	−2.75E−02	6.59E−03	−4.176	0.000111	***
GRN_X	3.59E−01	3.02E−02	11.894	<2.E−16	***
HCRT	6.85E−02	4.42E−03	15.497	<2.E−16	***
ICAM2	2.76E−02	3.57E−03	7.732	3.00E−10	***
IL-12A	6.05E−02	1.99E−02	3.041	0.003665	**
IL-17D	−2.49E−02	5.40E−03	−4.615	2.54E−05	***
LTA	6.29E+00	3.26E−01	19.289	<2.E−16	***
MMP25	−5.85E−01	9.19E−02	−6.367	4.69E−08	***
NGFR	−8.52E−03	4.98E−03	−1.710	0.093029	·
NLGN1_hu	−4.77E−01	2.24E−01	−2.125	0.038236	*
NLGN1_X	−1.19E−01	4.10E−02	−2.896	0.005486	**
NLGN4X	1.26E−01	2.50E−02	5.050	5.58E−06	***
NOG_hu	−9.37E−01	4.56E−02	−20.552	<2.E−16	***
NOG_X	−4.50E−01	1.34E−01	−3.356	0.001469	**
NPY_X	3.47E+00	2.24E−01	15.507	<2.E−16	***
NRG1_hu	7.93E−02	8.80E−03	9.013	2.80E−12	***
SERPING1	1.02E−01	8.17E−03	12.533	<2.E−16	***
SIGIRR	3.24E−02	4.02E−03	8.070	8.65E−11	***
SLC2A1	−2.15E−01	2.08E−02	−10.373	2.30E−14	***
SORL1_hu	1.08E+00	1.86E−01	5.796	3.82E−07	***
SPARC_hu1	−5.85E−02	8.72E−03	−6.712	1.31E−08	***
SPARC_hu2	−5.92E−01	8.40E−02	−7.044	3.84E−09	***
THBS4	2.05E−01	3.93E−02	5.226	2.98E−06	***
TIE1	−6.15E−02	8.83E−03	−6.960	5.22E−09	***
VEGFC	−1.39E+00	9.69E−02	−14.374	<2.E−16	***
WIF1	1.74E−01	1.44E−02	12.070	<2.E−16	***

^aSignificance codes: ***, <0.001; **, <0.01; *, <0.05; ·, <0.1. Residual standard errors, 0.1958 on 53 degrees of freedom; multiple R², 0.9897; adjusted R², 0.9815; F statistic, 120.9 on 42 and 53 degrees of freedom; P < 2.2E−16. Residuals: minimum, −0.43703; 1st quartile, −0.08250; median, −0.00196; 3rd quartile, 0.07220; maximum, 0.52013. AIC, −9.702973; BIC, 103.1283; Pr(>|t|), proportion of t distribution greater than t statistic.