TABLE 2.
Type-specific antibodies in chimeric FMDV-infected pigs determined by cross-virus neutralization
| Chimeric FMDV (infected pigs [n = 2]) | Reciprocal arithmetic titer for virus used in cross-VNT (pig 1/pig 2)a |
|||||||
|---|---|---|---|---|---|---|---|---|
| O Manisa | Om-O-PanAsia2 | Om-A22 | Om-AsMOG | Om-C-Ob | Om-SAT1-SA | Om-SAT2-SAU | Om-SAT3-SA | |
| O Manisa (223, 233) | 256/512 | 45/181 | —/— | —/— | —/— | —/— | —/— | —/— |
| Om-PanAsia2 (215, 235) | 128/256 | 724/512 | —/— | —/16 | —/— | —/— | —/— | —/— |
| Om-A22 (224, 236) | —/90 | —/128 | 256/90 | —/— | —/— | —/— | —/— | —/— |
| Om-AsMOG (200, 222) | 16/16 | 181/— | —/— | 181/90 | —/— | —/— | —/— | —/— |
| Om-C-Ob (212, 218) | —/— | —/— | —/— | —/— | 512/512 | —/— | —/— | —/— |
| Om-SAT1-SA (219, 220) | —/— | —/— | —/— | —/— | —/— | 181/512 | —/— | 16/— |
| Om-SAT2-SAU (291, 234) | —/— | —/— | —/— | —/— | —/— | —/— | 362/1,024 | —/— |
| Om-SAT3-SA (189, 217) | —/— | —/— | —/— | —/— | —/— | —/— | —/— | 362/181 |
a
VNT, virus neutralization test using sera from the pigs 12 days after infection with each chimeric FMDV. —, reciprocal titer of <16 (negative cutoff value for the virus neutralization test).