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. 2017 Jul 28;16:81. doi: 10.1186/s12940-017-0288-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Network of directional interactions between GWIS genes and in vitro transcriptomic genes. Round symbols represent genes identified by GWIS. Triangle symbols represent genes selected by in vitro transcriptomic assays, with upward triangles indicating Pb-induced genes and downward triangles indicating Pb-suppressed genes. Biological functions were annotated by NCBI, UCSC Genome Bioinformatics, and literature review