Table 2.
Cognitive status and Neuropsychiatric Inventory among dementia patients
| SIVD | AD | |||||
|---|---|---|---|---|---|---|
| All (n = 24) | CDR = 0.5 (n = 14) | CDR =1 ~ 2 (n = 10) | All (n = 32) | CDR = 0.5 (n = 21) | CDR = 1 ~ 2 (n = 11) | |
| MMSE£££ ǂ $$$ | 19.08 ± 5.04 | 21.07 ± 4.34 | 16.30 ± 4.79 | 21.03 ± 4.67 | 22.90 ± 3.75 | 17.45 ± 4.25 |
| CASI£££ ǂ $$$ | 61.04 ± 14.78 | 67.21 ± 13.16 | 52.40 ± 12.87 | 67.19 ± 15.20 | 73.29 ± 13.12 | 55.55 ± 12.04 |
| Total score | 6.42 ± 5.72 | 5.71 ± 6.33 | 7.40 ± 4.88 | 6.88 ± 8.87 | 5.19 ± 5.39 | 10.09 ± 12.98 |
| Hyperactivity | 0.51 ± 0.82 | 0.48 ± 0.94 | 0.55 ± 0.67 | 0.45 ± 0.89 | 0.18 ± 0.29 | 0.98 ± 1.35 |
| Agitation | 0.50 ± 1.45 | 0.64 ± 1.74 | 0.30 ± 0.95 | 0.38 ± 1.19 | 0.00 ± 0.00 | 1.09 ± 1.87 |
| Disinhibition | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.19 ± 1.06 | 0.00 ± 0.00 | 0.55 ± 1.81 |
| Irritability | 1.21 ± 1.82 | 1.29 ± 2.16 | 1.10 ± 1.29 | 0.91 ± 1.59 | 0.71 ± 1.15 | 1.27 ± 2.24 |
| Aberrant motor behavior | 0.33 ± 1.63 | 0.00 ± 0.00 | 0.80 ± 2.53 | 0.34 ± 1.15 | 0.00 ± 0.00 | 1.00 ± 1.84 |
| Psychosis | 0.58 ± 0.78 | 0.57 ± 0.86 | 0.60 ± 0.68 | 0.79 ± 1.19 | 0.65 ± 0.75 | 1.06 ± 1.78 |
| Delusion£ | 0.21 ± 0.72 | 0.00 ± 0.00 | 0.50 ± 1.08 | 0.63 ± 1.91 | 0.00 ± 0.00 | 1.82 ± 2.99 |
| Hallucination | 0.08 ± 0.41 | 0.00 ± 0.00 | 0.20 ± 0.63 | 0.31 ± 1.15 | 0.10 ± 0.44 | 0.73 ± 1.85 |
| Night-time behavior | 1.46 ± 2.27 | 1.71 ± 2.59 | 1.10 ± 1.79 | 1.44 ± 1.97 | 1.86 ± 2.10 | 0.64 ± 1.43 |
| Affective | 0.63 ± 1.10 | 0.79 ± 1.25 | 0.40 ± 0.84 | 1.08 ± 1.41 | 1.05 ± 1.40 | 1.14 ± 1.50 |
| Depression | 0.58 ± 1.25 | 0.57 ± 1.22 | 0.60 ± 1.35 | 0.88 ± 1.50 | 0.76 ± 1.14 | 1.09 ± 2.07 |
| Anxiety | 0.67 ± 1.52 | 1.00 ± 1.88 | 0.20 ± 0.63 | 1.28 ± 2.33 | 1.33 ± 2.20 | 1.18 ± 2.68 |
| Apathy £ǂǂ | 0.65 ± 0.89 | 0.25 ± 0.80 | 1.20 ± 0.72§§ | 0.23 ± 0.51 | 0.21 ± 0.46 | 0.27 ± 0.61§§ |
| Apathy ££ǂǂ | 0.96 ± 1.43* | 0.07 ± 0.27 | 2.20 ± 1.48§§ | 0.25 ± 0.62* | 0.29 ± 0.72 | 0.18 ± 0.41§§ |
| Eating abnormalities | 0.33 ± 1.27 | 0.43 ± 1.60 | 0.20 ± 0.63 | 0.22 ± 0.87 | 0.14 ± 0.66 | 0.36 ± 1.21 |
(1) Mean ± SD were shown. (2) Abbreviation: SIVD subcortical ischemic vascular disease, AD Alzheimer’s disease, CDR Clinical Dementia Rating, MMSE Mini-Mental State Examination, CASI Cognitive Abilities Screening Instrument, Sig. Significance.(3) T-test was used to evaluate the group difference and significant difference was defined as p value <0.05. (4) * p < 0.05 on the comparisons between all SIVD patients and all AD patients;# p < 0.05 on the comparisons between SIVD patients with CDR score = 0.5 and AD patients with CDR score = 0.5; § p < 0.05, §§ p < 0.01 on the comparisons between SIVD patients with CDR score = 1 ~ 2 and AD patients with CDR score = 1 ~ 2. (5) £ p < 0.05, ££ p < 0.01, and £££ p < 0.001 on the comparisons between patient with CDR score = 0.5 and with CDR score = 1 ~ 2 among all patients respectively. (6) ǂ p < 0.05 and ǂǂ p < 0.01 on the comparisons between patient with CDR score = 0.5 and with CDR score = 1 ~ 2 in SIVD group respectively. (7) $$$ p < .001 on the comparisons between patient with CDR score = 0.5 and with CDR score = 1 ~ 2 in AD group