Fig. 1.

The effect of ECMO on physiological parameters. Temperature remained constant a, while S-ALI controls and S-ALI + ECMO animals had a decreased pH b. Ionised calcium levels c and the circuit flow rate d were decreased in S-ALI + ECMO compared with healthy controls. Data are presented as mean ± SEM. *P < 0.05, ***P < 0.001 versus healthy controls. n = 4 healthy controls, n = 8 ECMO controls, n = 7 S-ALI controls, n = 8 S-ALI + ECMO. ECMO Extracorporeal membrane oxygenation, S-ALI Smoke-induced acute lung injury, B Baseline