Table 3.
Associations among PD-L1, PD-L2, PD-1 expression, and CD8(+) T-cell density in primary tumors from patients with gastric adenocarcinoma
| Variable | PD-L1 expression [cases (%)] | PD-L2 expression [cases (%)] | ||||
|---|---|---|---|---|---|---|
| Negative | Positive | P | Negative | Positive | P | |
| PD-L2 expression | 0.043 | |||||
| Negative | 57 (47.9) | 28 (23.5) | ||||
| Positive | 16 (13.4) | 18 (15.1) | ||||
| Density of CD8(+) T cells | 0.022 | 0.004 | ||||
| Low | 22 (18.5) | 24 (20.2) | 26 (21.8) | 20 (16.8) | ||
| High | 51 (42.9) | 22 (18.5) | 59 (49.6) | 14 (11.8) | ||
| PD-1 expression on CD8(+) T cells | 0.162 | 0.951 | ||||
| Negative | 49 (41.2) | 25 (21.0) | 53 (44.5) | 21 (17.6) | ||
| Positive | 24 (20.2) | 21 (17.6) | 32 (26.9) | 13 (10.9) | ||