Figure 2.

Sensitivity analysis of model parameters. Frequency distributions of the relative nucleotide substitution rate at the population level in the immunocompromised population compared to the general population $\left(K_c\right)$ from sampling 1000 points of the parameter space using Latin Hypercube Sampling. Panels (a–c) $1/{\gamma }_c=$1 month; Panels (d–f) $1/{\gamma }_c=12$ months. Panels (a,d) $q=0.1$; Panels (b,e) $q=0.5$; Panels (c,f) $q=0.9$. In all cases, $1/\gamma =7$ days, $N={10}^6$, $1/{\theta }_c=3 \text{days}$, and $k_c/k=1$.