Table 3.

Comparison of Psoriasis Patients Stratified by Non-Calcified Burden

Variable*	Lower NCB‡ than median (N=52)	Higher NCB‡ than median (N=53)	P†
Demographic and Clinical History
Age, years	49.6±11.8	50.7±12.9	0.63
Male, %	23 (44.2%)	42 (79.3%)	<0.001
Hypertension, %	11 (21.1%)	21 (39.6%)	0.04
Dyslipidemia, %	21 (40.4%)	31 (58.5%)	0.06
Diabetes Mellitus, %	7 (13.2%)	5 (9.4%)	0.52
Current smoking, %	5 (9.6%)	3 (5.7%)	0.45
Clinical parameters:
Body Mass Index, kg/m2	27.1±3.9	32.5±6.3	<0.001
Systolic BP, mm Hg	119.8±11.8	129.5±15.9	<0.001
Diastolic BP, mm Hg	70.3±7.6	76.5±12.5	0.002
Framingham 10-year risk score	3 (1–6)	4 (2–7)	0.11
Atherosclerotic cardiovascular disease (ASCVD) 10-year risk	2.7 (1.2–7.8)	4.9 (2.5–10.2)	0.02
Statin Therapy	11 (21.1%)	24 (45.2%)	0.01
Lipid profile:
Total cholesterol, mg/dL	188.2±36.5	174.8±39.7	0.04
Low-density lipoprotein cholesterol, mg/dL	102.6±32.7	99.0±32.4	0.58
High-density lipoprotein cholesterol, mg/dL	61.4±21.0	50.2±14.4	0.001
Triglycerides, mg/dL	92.5 (67.5–134.5)	108.0 (84–174)	0.15
Glucose, mg/dL	99.5±21.1	102.9±13.9	0.34
Psoriasis Characteristics
Psoriasis Area Severity Index Score	4.8 (2.4–8.4)	6.1 (3.2–12.2)	0.28
Systemic/Biologic Treatment, %	24 (46.1%)	14 (26.4%)	0.04
Coronary plaque burden:
Total Burden (× 100), mm2	0.90±0.22	1.54±0.43	<0.001
Non-Calcified Burden (× 100), mm2	0.85±0.22	1.50±0.43	<0.001
Dense-Calcified Burden (×100), mm2	0.05±0.07	0.04±0.07	0.69
Coronary Plaque Characterization
Presence of High-Risk Plaque, %	10 (19.2%)	26 (49.0%)	0.001
Average Number of High-Risk Plaques	0.43±1.23	0.74±1.08	0.08

^*All values in table 3 are represented as mean ± SD or median (IQR) for continuous variables and as n (%) for categorical variables.

^†P values were calculated by Student’s t-test or Mann-Whitney U test for continuous variables and by Pearson’s chi-square test for categorical variables.

^‡NCB: non-calcified burden