Table 3.

Main themes and subthemes

Main theme	Subtheme
Symptom alleviation	Pain throughout the body Physical and mental fatigue Itching, flaking skin Inflammation, swelling and stiffness Reducing variability
Reduction of disease impact	Overwhelming tiredness and pain Limited mobility and dexterity Deteriorating physical fitness Poor quality and disrupted sleep Negative emotional responses Strained relationships and social interactions
Improved prognosis	Slowing down or halting disease progression Enabling independence to be maintained Enhancing quality of life, well-being and sense of normality
Minimisation of harm and burden	Nausea and sickness Concerns about long-term effects Modes of administration Monitoring requirements