Table 2.

List of up-regulated genes differentially expressed by ≥twofold with a P < 0.05 obtained after the 10 % cocoa diet intake (C10 group) compared to the REF group (n = 4/group)

Symbol	C10 vs REF	CF vs REF	I vs REF
	log2 FC	log2 FC	log2 FC
Scgb1a1	3.948	1.716	1.139
Scnn1g	3.119	1.133	0.573
Fxyd4	2.583	2.089	0.718
Slc15a1	2.332	1.388	0.475
Gbp1	2.207	1.662	0.432
Cyp2f4	2.185	1.436	0.367
Dpysl4	2.069	1.387	0.242
Fmo2	2.040	1.007	0.426
Pdyn	1.873	0.194	0.175
Mt2A	1.656	0.644	−0.147
RGD1561239	1.597	1.787	0.742
Sftpd	1.583	0.163	0.351
Mme	1.580	0.636	0.353
Hoxd13	1.575	0.615	0.100
Chst5	1.533	0.591	0.082
Atp12a	1.457	1.630	0.500
Thbs4	1.450	0.908	0.302
Hoxd10	1.403	0.668	0.164
Trpv1	1.390	0.749	0.058
Hoxb13	1.358	0.786	0.101
Spink3	1.338	1.162	0.463
LOC687303	1.327	0.734	0.755
Abat	1.319	1.272	0.477
Angptl4	1.316	0.914	0.670
Aox4	1.311	0.054	0.320
B3gnt7	1.265	0.403	0.019
Pcsk9	1.253	0.048	0.063
RGD1560608	1.225	0.759	0.709
Guca2b	1.211	0.811	0.287
Padi3	1.190	0.832	0.462
Scnn1b	1.181	0.499	0.057
LOC287167	1.178	0.607	0.296
RGD1308274	1.142	0.073	0.321
Smc1b	1.133	0.968	0.031
Pde7a	1.129	0.708	0.405
LOC100363350	1.126	0.621	0.446
Gsta2	1.111	0.537	0.157
Slc20a1	1.110	0.624	0.056
RGD1310110	1.097	0.410	0.231
LOC689064	1.095	1.024	0.501
Rnase1	1.094	1.063	1.218
Dnase1	1.088	1.087	0.124
siat7D	1.058	0.363	0.096
Serpinc1	1.053	0.873	0.469
LOC494499	1.029	0.576	0.276
Fbxl13	1.028	1.009	0.067
Alox15	1.028	0.387	0.191
Creg1	1.021	0.406	− 0.008
Rnase1l2	1.010	0.857	1.012
Alas2	1.007	0.997	0.452

This includes the gene symbol for all the up-regulated genes. Values are expressed as a log2 of fold change and shown when ≥1. Values for the two other experimental diets are also included, although independently of their fold change and/or their significance. Values in bold and cursive represent the non-statistically significant changes