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. 2017 Jul 16;2017:6294717. doi: 10.1155/2017/6294717

Figure 2.

Figure 2

MSC treatment reduces influx of DCs, macrophages, and CD4+ T cells, in the metastatic model of lung cancer, and altered their cytokine profile. Total numbers of (a) CD45+, (b) CD45+ F4/80+, (c) CD45+ CD11c+ CD11b+, and CD11c+ TNF-α+ cells in the lungs of control, LLC1, and LLC1 + MSC-treated mice at the 28th day of the experiment. (d) Total number and representative flow cytometry dot plots of CD4+, TNF-α-, and IL-17-producing CD4+ cells at the 28th day of the experiment. (e) Total numbers of lung-infiltrating CD4+ IL-10+ cells at the 28th day of the experiment. Values are mean ± SEM (n = 10  per  group). ∗p < 0.05, ∗∗p < 0.01.