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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: J Mol Cell Cardiol. 2016 Jul 2;99:174–187. doi: 10.1016/j.yjmcc.2016.06.068

Figure 5.

Figure 5

Effects of NCX1 localization on spark properties in the whole-cell model. The role of NCX1 distribution between cytosol and dyad only (fd+pd = fd since fpd = 0, solid lines), between cytosol and PD only (fd+pd = fpd since fd = 0, dashed lines), or among all three compartments with a fd:fpd ratio of 1:2 (fd+pd = fd + fpd with fpd = 2fd, dotted lines) on whole-cell spark rate (A), peak [Ca2+]d (B), spark duration measured as FDHM (C), and diastolic [Ca2+]d (D). The total number of NCX1s in the cell is the same in all cases.