Table I.
Demographics of Angelman syndrome study cohort.
| Full Cohort | Known Genotype | ||
|---|---|---|---|
| % (n=109) | % (n=93) | p-valuea | |
|
|
|||
| Mean age | 24.3y (sd: 7.24) | 24.3 y (sd: 7.46) | 0.895b |
| 16–20y | 38% | 38% | 1.000 |
| 21–25y | 27% | 28% | 0.552 |
| 26–30y | 21% | 19% | 0.322 |
| 31–40y | 11% | 11% | 0.689 |
| 41–50y | 4% | 4% | 1.000 |
| Sex | |||
| Female | 50% | 51% | 0.788 |
| Male | 50% | 49% | |
| Interviewee | |||
| Mother | 89% | 89% | 0.689 |
| Father | 6% | 5% | 0.273 |
| Both | 2% | 2% | 1.000 |
| Other | 3% | 3% | 1.000 |
| Genotype | |||
| Maternal deletion | 68% | 80% | -- |
| UBE3A mutation | 8% | 10% | -- |
| UPD | 9% | 11% | -- |
| Mosaic | Single case | -- | -- |
| Clinical | 10% | -- | -- |
| Unknown | 5% | -- | -- |
| Home environment | |||
| Parents’ home | 75% | 74% | 0.756 |
| Group home | 17% | 16% | 0.731 |
| Residential center | 6% | 7% | 0.588 |
| Other | 3% | 3% | 1.000 |
a
2-sided Fisher’s Exact Test.
b
Independent Samples T-Test/Levene’s Test for Equality (Sig. 0.510). y: years, UPD: uniparental disomy.