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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Mol Pharm. 2017 Apr 4;14(5):1591–1600. doi: 10.1021/acs.molpharmaceut.6b01028

Figure 9.

Figure 9

The neuroprotective effect of NAC-NPs under a co-culture model. Confocal images of BV-2 cells (green) with SHSY5Y cells (red) receiving different treatments (A) and the percentage of engulfed SHSY5Y cells under co-culture (B). LPS-induced microglia phagocytosis of SHSY5Y cells visualized by confocal microscopy after 24 hours of co-culture of BV-2 cells with SHSY5Y cells. BV-2 cells were treated with either free NAC or NAC-NPs at the NAC equivalent concentration of 2.5 mM in the presence of LPS 100 ng/ml for 24 hours. Arrows indicate the overlapping of red and green signals. Data expressed as mean ± SD (* P < 0.05).