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. 2017 Jul;33(4):329–338. doi: 10.6515/ACS20161205A

Table 1. Summary of 10 papers published from the Taiwan ACS full spectrum registry.

Year Titles Study questions Conclusions References
2011 Clinical characteristics, management and in-hospital outcomes of patients with acute coronary syndrome - observations from the Taiwan ACS full spectrum registry Current practices in ACS management, adherence to guidelines and in-hospital outcomes Median DTN and DTB times were higher. 3
Secondary preventive therapy during the in-hospital stay and at discharge were suboptimal.
There is a need to close the gap between the guidelines and the actual ACS clinical management in Taiwan.
2013 Effects of clopidogrel on mortality, cardiovascular and bleeding outcomes in patients with chronic kidney disease - data from Taiwan acute coronary syndrome full spectrum registry The efficacy and safety of clopidogrel in patients with ACS and CKD Clopidogrel could decrease mortality and improve cardiovascular outcomes without increasing risk of bleeding in ACS patients with CKD. 18
2014 Predictors of 1-year outcomes in the Taiwan acute coronary syndrome full spectrum registry Evaluate the ACS management and identify the predictors of clinical outcomes of death/myocardial infarction/stroke 1 year post hospital discharge Policy adherence, especially with regard to dual antiplatelet therapy may hold the key to long-term favorable outcomes and improved survival rates in ACS patients in Taiwan. 13
2014 Impact of impaired glomerular filtration rate and revascularization strategy on one-year cardiovascular events in acute coronary syndrome: data from Taiwan acute coronary syndrome full spectrum registry The prognosis and impact of IGFR and invasive strategy on the cardiovascular outcomes in the ACS population IGFR patients suffering from ACS had poor prognosis. 21
An invasive strategy could improve cardiovascular outcome in the NSTE-ACS population.
2014 Use of CHADS2 and CHA2DS2-VASc scores to predict subsequent myocardial infarction, stroke, and death in patients with acute coronary syndrome: data from Taiwan acute coronary syndrome full spectrum registry Whether CHADS2 and CHA2DS2-VASc scores were useful tools to assess the risk for adverse events among ACS patients CHADS2 and CHA2DS2-VASc score were useful predictors of subsequent adverse events in ACS patients. 28
2015 Additive effect of in-hospital TIMI bleeding and chronic kidney disease on 1-year cardiovascular events in patients with acute coronary syndrome: data from Taiwan acute coronary syndrome full spectrum registry Whether increased risk of CVE by IHB is influenced by CKD or both have detrimental effects on CVE IHB or CKD is independently associated with poor cardiovascular outcome. 36
Patients with both IHB and CKD have the worst outcome in ACS.
2015 Effects of door-to-balloon times on outcomes in Taiwanese patients receiving primary percutaneous coronary intervention: a report of Taiwan acute coronary syndrome full spectrum registry The relationship between stratified DTB time and outcomes DTB time is not a good determinant for outcomes in Taiwanese patients receiving primary PCI. 47
2016 Prognostic impact of renal dysfunction in patients with acute coronary syndrome-role beyond the CHA2DS2-VASc score: data from Taiwan acute coronary syndrome full spectrum registry Whether the addition of renal dysfunction in the CHA2DS2-VASc score would improve the prognostic impact of the scoring system to predict prognosis among ACS patients Renal dysfunction is a significant risk factor of future adverse events in ACS patients and may improve the prognostic impact of the CHA2DS2-VASc score. 32
2016 The relation between the timing of percutaneous coronary intervention and outcomes in patients with acute coronary syndrome with routine invasive strategy - data from Taiwan acute coronary syndrome full spectrum data registry Optimal timing for high-risk NSTE-ACS patients PCI within 24-72 hours from symptom onset is demonstrably the optimum time for high-risk NSTE-ACS patients. 55
Delayed PCI over 72 hours is associated with the worst outcomes and should be avoided.
For patients with low risks, routine early PCI < 24 hours after PCI is not beneficial.
2016 Diabetes and adverse cardiovascular outcomes in patients with acute coronary syndrome - data from Taiwan's acute coronary syndrome full spectrum data registry The effect of Diabetes on adverse cardiovascular outcomes in ACS patients Compared to patients without Diabetes, ACS patients with diabetes had significantly worse outcomes in terms of all-cause death and the combined results for death, re-infarction and stroke. 60

ACS, acute coronary syndrome; CKD, chronic kidney disease; CVE, cardiovascular events; DTB, door-to-balloon; DTN, door-to-needle; IGFR, impaired glomerular filtration rate; IHB, in-hospital bleeding; NSTE-ACS, non-ST-elevation acute coronary syndrome; PCI, percutaneous coronary Intervention; TIMI, thrombolysis in myocardial infarction.