Supplemental Table 3. Subgroup analysis of STEMI patients with vs. without cardiogenic shock.
| Variables | With cardiogenic shock | Without cardiogenic shock | ||||
| BID ≤ 9 times (N = 105) | BID > 9 times (N = 55) | p | BID ≤ 9 times (N = 34) | BID > 9 times (N = 12) | p | |
| Age (years) | 68 (55-80) | 67 (59-77) | 0.931 | 59 (53-67) | 60 (51-72) | 0.871 |
| Body mass index (kg/m2) | 24.8 (22.2-27.2) | 23.8 (22.0-26.6) | 0.363 | 24.2 (22.7-27.4) | 24.5 (22.0-26.4) | 0.797 |
| Creatinine (mg/dl) | 1.1 (0.8-1.4) | 1.1 (0.8-1.7) | 0.698 | 1.3 (0.9-1.6) | 1.2 (0.9-1.6) | 0.774 |
| Hemoglobin (g/dl) | 13.8 (12.0-15.3) | 13.7 (11.7-15.2) | 0.748 | 14.9 (13.0-15.9) | 13.6 (10.3-15.3) | 0.118 |
| CAD risk factors | ||||||
| Male | 31 (29.5) | 18 (32.7) | 0.720 | 3 (8.8) | 4 (33.3) | 0.064 |
| Current/past smoker | 43 (41.0) | 30 (54.5) | 0.132 | 23 (67.6) | 3 (25.0) | 0.017 |
| Hypertension | 75 (71.4) | 41 (74.5) | 0.852 | 14 (41.2) | 3 (25.0) | 0.489 |
| Diabetes | 53 (50.5) | 26 (47.3) | 0.739 | 24 (70.6) | 5 (41.7) | 0.093 |
| Hyperlipidemia | 33 (31.4) | 12 (21.8) | 0.266 | 8 (23.5) | 2 (16.7) | 1.000 |
| Known CAD | 16 (15.2) | 9 (16.4) | 1.000 | 4 (11.8) | 3 (25.0) | 0.355 |
| Previous MI | 4 (3.8) | 3 (5.5) | 0.699 | 2 (5.9) | 1 (8.3) | 1.000 |
| Ischemic stroke | 11 (10.5) | 6 (10.9) | 1.000 | 4 (11.8) | 2 (16.7) | 0.644 |
| Killip class | ||||||
| I | 55 (52.4) | 23 (41.8) | 0.245 | 0 (0) | 0 (0) | - |
| II | 41 (39.0) | 22 (40.0) | 1.000 | 0 (0) | 0 (0) | - |
| III | 10 (9.5) | 9 (16.4) | 0.120 | 0 (0) | 0 (0) | - |
| IV | 0 (0) | 0 (0) | - | 34 (100.0) | 12 (100.0) | - |
| Mehran risk score | ||||||
| Hypotension | 0 (0) | 0 (0) | - | 34 (100.0) | 12 (100.0) | - |
| IABP support | 27 (25.7) | 17 (30.9) | 0.576 | 22 (64.7) | 7 (58.3) | 0.737 |
| Congestive heart failure | 7 (6.7) | 9 (16.4) | 0.093 | 0 (0.0) | 0 (0.0)0 | - |
| Age > 75 (years) | 39 (37.1) | 19 (34.5) | 0.863 | 4 (11.8) | 2 (16.7) | 0.644 |
| Anemia | 35 (33.3) | 19 (34.5) | 1.000 | 7 (20.6) | 4 (33.3) | 0.441 |
| Procedural characteristics | ||||||
| Numbers of BID performed | 6 (4-7) | 13 (12-17)0 | < 0.001 | 5 (4-7) | 16 (12-19) | < 0.001 |
| Contrast volume (ml) | 155 (150-200) | 200 (175-265) | < 0.001 | 180 (150-200) | 260 (165-280) | 0.022 |
| Fluoroscopy times (min)* | 10.8 (8.8-13.7) | 17.6 (13.4-25.4) | < 0.001 | 11.2 (8.4-16.0) | 20.6 (13.3-25.8) | 0.018 |
| Door-to-balloon time (min) | 74 (60-110) | 77 (63-110) | 0.519 | 77 (60-96) | 112 (85-141) | 0.040 |
| Trans-femoral approach | 96 (91.4) | 44 (80.0) | 0.046 | 33 (97.1) | 11 (91.7) | 0.458 |
| Thrombus aspiration | 66 (62.9) | 25 (45.5) | 0.044 | 14 (41.2) | 7 (58.3) | 0.335 |
| Glycoprotein IIb/IIIa inhibitor | 65 (61.9) | 31 (56.4) | 0.503 | 18 (52.9) | 8 (66.7) | 0.509 |
| IABP support | 10 (9.5) | 5 (9.1) | 0.701 | 10 (29.4) | 5 (41.7) | 0.488 |
| Multiple-vessel disease | 69 (65.7) | 48 (87.3) | 0.004 | 24 (70.6) | 9 (75.0) | 1.000 |
| Infarct-related artery | ||||||
| LAD | 51 (48.6) | 24 (43.6) | 0.618 | 16 (47.1) | 5 (41.7) | 1.000 |
| Non-LAD | 0 (0) | 0 (0) | - | 0 (0) | 0 (0) | - |
| LM | 1 (1.0) | 0 (0) | 1.000 | 0 (0) | 1 (8.3) | 0.261 |
| Stent implantation | 88 (83.8) | 53 (96.4) | 0.021 | 30 (88.2) | 11 (91.7) | 1.000 |
| Bare-metal stent | 83 (79.0) | 45 (81.8) | 0.836 | 27 (79.4) | 11 (91.7) | 0.660 |
| Drug-eluting stent | 5 (4.8) | 9 (16.4) | 0.035 | 3 (8.8) | 0 (0.0) | 0.557 |
| Number of stent implantations | ||||||
| 1 | 69 (65.7) | 18 (32.7) | < 0.001 | 26 (76.5) | 4 (33.3) | 0.013 |
| 2 | 18 (17.1) | 23 (41.8) | < 0.001 | 4 (11.8) | 4 (33.3) | 0.178 |
| 3 | 1 (1.0) | 10 (18.2) | < 0.001 | 0 (0) | 3 (25.0) | 0.014 |
| 4 | 0 (0) | 3 (5.5) | 0.039 | 0 (0) | 0 (0) | - |
| Initial TIMI flow | ||||||
| 0 | 80 (76.2) | 30 (54.5) | 0.007 | 26 (76.5) | 9 (75.0) | 1.000 |
| 1 | 7 (6.7) | 5 (9.1) | 0.753 | 1 (2.9) | 2 (16.7) | 0.162 |
| 2~3 | 18 (17.1) | 20 (36.4) | 0.010 | 6 (17.6) | 1 (8.3) | 0.657 |
| Final TIMI flow | ||||||
| 0 | 2 (1.9) | 0 (0) | 0.546 | 1 (2.9) | 0 (0) | 1.000 |
| 1 | 2 (1.9) | 0 (0) | 0.546 | 0 (0) | 0 (0) | 1.000 |
| 2~3 | 101 (96.2) | 55 (100.0) | 0.300 | 2 (5.9) | 0 (0) | 1.000 |
| PCI to non-IRA | 2 (1.9) | 2 (3.6) | 0.608 | 1 (2.9) | 1 (8.3) | 0.467 |
| Heavy calcification of IRA | 29 (27.6) | 12 (21.8) | 1.000 | 4 (11.8) | 0 (0.0) | 0.561 |
| IRA lesion > 20mm | 85 (81.0) | 48 (87.3) | 0.378 | 30 (88.2) | 10 (83.3) | 0.598 |
| Bifurcation lesion of IRA | 68 (64.8) | 37 (67.3) | 0.642 | 21 (61.8) | 9 (75.0) | 0.330 |
| Side branch > 1.5mm | 40 (38.1) | 25 (45.5) | 14 (41.2) | 8 (66.7) | ||
| Side branch < 1.5mm | 28 (26.7) | 12 (21.8) | 7 (20.6) | 1 (8.3) | ||
| Periprocedural complications | ||||||
| Any dissection | 54 (51.4) | 27 (49.1) | 0.868 | 15 (44.1) | 9 (75.0) | 0.101 |
| Type D dissection | 4 (3.8) | 5 (9.1) | 0.277 | 3 (8.8) | 0 (0.0) | 0.553 |
| Type F dissection | 11 (10.5) | 5 (9.1) | 1.000 | 32 (94.1) | 11 (91.7) | 0.467 |
| Outcome | ||||||
| CIAKI | 8 (7.6) | 8 (14.5) | 0.176 | 2 (5.9) | 5 (41.7) | 0.009 |