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. 2017 May 23;7(5):e1137. doi: 10.1038/tp.2017.104

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Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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[1H]MRS voxel positions and example spectra. (a) Cortical region of interest; medial prefrontal cortex (mPFC) (25 × 30 × 40 mm³) outlined in white, comprising primarily of anterior cingulate cortex. (b) Example spectroscopy output from the prefrontal voxel (Glx (glutamate+glutamine); GABA; N-acetylaspartate (NAA) identified using jMRUI spectroscopy software.