Table 1. Demographic characteristics of dementia cases and controls.
| No dementia (n=11 975) | All dementia (n=1256) | Alzheimer'sdisease (n=741) | Vascular demented (n=273) | |
|---|---|---|---|---|
| Age at baseline, mean (s.d.) | 50.7 (2.8) | 54.7 (5.7)a | 54.8 (5.8)a | 54.6 (5.6)a |
| Age at death, mean (s.d.) | 81.5 (9.2) | 86.0 (6.2)a | 86.5 (6.2)a | 85.5 (5.8)a |
| Follow up time, mean (s.d.) | 22.8 (8.3) | 25.2 (7.0)a | 25.1 (6.9)a | 25.0 (6.4)a |
| GRS for CAD, mean (s.d.) | 53.9 (4.4) | 53.5 (4.3)a | 53.6 (4.4)a | 53.4 (4.2) |
| Female sex, n (%) | 6206 (52.6) | 840 (59.7)a | 548 (63.1)a | 149 (47.8) |
| Low education, n (%) | 3877 (33.0) | 840 (58.9)a | 492 (56.9)a | 187 (60.1)a |
| Non-stroke CVD, n (%) | 2324 (19.7) | 306 (21.4) | 148 (17.1) | 90 (28.9)a |
| Prior stroke, n (%)b | 1057 (9.0) | 241 (16.9)a | 65 (7.5) | 122 (39.1)a |
| Diabetes, n (%)b | 1145 (9.7) | 167 (11.7)a | 81 (9.3) | 46 (14.7)a |
Abbreviations: CAD, coronary artery disease; CVD, cardiovascular disease; GRS, genetic risk score.
a
Significant difference compared with the no dementia group (P<0.05) based on chi-square test for binary variables and t-test for continuous variables.
b
Stroke and diabetes before dementia onset.
Number of exposed individuals (percent of number of individuals with covariate data) for binary variables, and mean age (standard deviation) for continuous variables.