Table 2. Hazard ratios of dementia in relation to genetic risk of coronary artery disease.

	All dementia	Alzheimer's disease	Vascular dementia
GRS for CAD	1.01 (1.00–1.02)	1.01 (0.99–1.03)	1.01 (0.98–1.04)
1st quartile	1.00	1.00	1.00
2nd quartile	0.99 (0.85–1.14)	0.96 (0.78–1.18)	0.98 (0.71–1.36)
3rd quartile	1.05 (0.90–1.22)	0.96 (0.78–1.19)	1.18 (0.86–1.62)
4th quartile	1.10 (0.95–1.29)	1.20 (0.98–1.48)	0.85 (0.59–1.24)

Abbreviations: CAD, coronary artery disease; GRS, genetic risk score.

Hazard ratios (95% confidence intervals) of dementia/Alzheimer's disease in relation to genetic risk of CAD, both as continuous measure and categorized into quartiles. The model is adjusted for age, sex, education and diabetes before dementia onset.