Table 1. Population characteristics.
General characteristics | % (N) or median (25th,75th) |
---|---|
Age (years) | 18.9 (18.5, 19.4) |
Female sex | 54.3 (590) |
Inflammatory status at age 16 | |
hsCRP >2 mg l−1 | 12.3 (130) |
HSV1 seropositivity | 23.7 (258) |
HSV1 antibodies (AU) in positive group | 2.08 (1.68, 2.54) |
EBV seropositivity | 24.2 (263) |
EBV antibodies (AU) in positive group | 1.31 (1.19, 1.51) |
CMV seropositivity | 24.5 (266) |
CMV antibodies (AU) in positive group | 2.17 (1.95, 2.45) |
Psychiatric disorders in the previous year at age 19 | |
Any mood disorder, including: | 10.5 (112) |
N (%) within mood disorders | |
Bipolar I | 3.6 (4) |
Bipolar II | 9.8 (11) |
Major depressive disorder | 84.8 (95) |
Dysthymia | 18.8 (21) |
N (%) of total population | |
1 disorder | 7.5 (82) |
2 disorders | 2.8 (28) |
3 disorders | 0.2 (2) |
Any anxiety disorder, including: | 11.4 (124) |
N (%) within anxiety disorders | |
Generalized anxiety disorder | 20.2 (25) |
Panic disorder | 8.9 (11) |
Social phobia | 62.9 (78) |
Obsessive compulsive disorder | 29.8 (37) |
N (%) of total population | |
1 disorder | 9.1 (99) |
2 disorders | 2.1 (23) |
3 disorders | 0.2 (2) |
Comorbid mood and anxiety disorder | 3.4 (37%) |
Life events before age 16 | |
Life events score | 3.7 (3.2, 4.5) |
Life events z-score | −0.4 (−1.7, 1.3) |
Covariates | |
Dutch ethnicity | 90.5 (984) |
SES low | 16.9 (184) |
SES average | 48.4 (526) |
SES high | 33.9 (368) |
BMI (kg/m2) | 20.77 (19.24, 22.53) |
Percentage that used nicotine in past 4 weeks | 27.4 (298) |
Percentage that used alcohol in past 4 weeks | 75.1 (816) |
Abbreviations: AU, arbitrary unit; BMI, body mass index; CMV, cytomegalovirus antibody levels; EBV, Epstein–Barr virus antibody levels; hsCRP, high-sensitive C-reactive protein; HSV1, herpes simplex virus type 1 antibody levels; SES, categorical measurement of socioeconomic status.
Life events score was computed by adding the mean scores on the various trauma types.